hrp0095p2-238 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Rare causes of hypopituitarism in children

Akulevich Natallia , Kuzmenkova Elena , Solntseva Anzhelika

Background: Septo-optic dysplasia (SOD) is characterized by two or more features of the triad: optic nerve (ON) hypoplasia, middle brain defects and pituitaty deficiencies. Pituitary Stalk Interruption Syndrome (PSIS) presents as a lack of a visible pituitary stalk and/ or no eutopic posterior lobe hypersignal in the shallow sella turcica. Both conditions usually result in hypopituitarism. The diagnosis is based on clinical signs and MRI findings; only small n...

hrp0092p3-191 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Hormone-Secreting Pituitary Adenomas in Children and Adolescents

Akulevich Natallia , Kuzmenkova Elena , Zhuravlev Vladimir , Solntsava Anzhalika

Background: Hormone-secreting pituitary adenomas in children and adolescents are rare.Methods: We report clinical course, management and outcome of 6 cases diagnoses in 2013-2019.Results: Patients (3M, 3F), aged 9,5 – 16,5 years at referral. In them, 3 ACTH-secreting adenomas (ACTHA) and 3 prolactinomas (PROLA) were recognized. The family history for endocrine tumors was negat...